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Current problems of perinatal Chlamydia trachomatis infections

Kei Numazaki email

Department of Pediatrics, Sapporo Medical University School of Medicine, Sapporo, Japan

author email corresponding author email

Journal of Immune Based Therapies and Vaccines 2004, 2:4doi:10.1186/1476-8518-2-4

Published: 13 February 2004

Abstract

Chlamydia trachomatis has been recognized as a pathogen of trachoma, nongonococcal urethritis, salpingitis, endocervicitis, pelvic inflammatory disease, inclusion conjunctivitis of neonates, follicular conjunctivitis of adults, infantile pneumonia and associated conditions. Chlamydial infections during pregnancy may also cause a variety of perinatal complications. Different antigenic strains of C. trachomatis from endocervical, nasopharyngeal and conjunctival origins have been associated with different clinical conditions. Control programs emphasizing early diagnosis, targeted screening, and effective treatment will lead to an eventual decline in the incidence of perinatal chlamydial infection. This review focuses on current problems of perinatal C. trachomatis infections in the aspects of microbiological and immunological pathogenesis.


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