Table 1

Isotype specific antibodies and streptavidin-PE used in the HPV antibody isotyping assays

Isotype Reagent
Type or MAb Identity
Specificity
Source
Supplier
Concentration

Primary





IgM
polyclonal
Monkey IgM (mu chain specific)
Goat
Rockland, Gilbertsville, PA
50 μg/mL
IgA
polyclonal
Monkey IgA (alpha chain specific)
Goat
Rockland, Gilbertsville, PA
25 μg/mL
IgE
HP-6029
Human IgE (epsilon chain specific)
Mouse
Southern Biotech, Birmingham, AL
25 μg/mL
IgG1
HP-6091or 8c/639
Human IgG1
Mouse
Sigma, St. Louis, MO
10 μg/mL
IgG2
HP-6014
Human IgG2
Mouse
Sigma, St. Louis, MO
10 μg/mL
IgG4
HP-6025
Human IgG4
Mouse
Sigma, St. Louis, MO
25 μg/mL
Total IgG
polyclonal
Monkey IgG (gamma chain specific)
Goat
Rockland, Gilbertsville, PA
5 μg/mL
Secondary





PE- Streptavidin
NA
NA
NA
Rockland, Gilbertsville, PA
5 μg/mL

Ruiz et al. Journal of Immune Based Therapies and Vaccines 2005 3:2   doi:10.1186/1476-8518-3-2