Table 2 |
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|
Recovery of S. aureus from peritoneal fluid obtained from mice challegened with live S. aureus |
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| Bacterial challenge (CFU) |
106 |
107 |
108 |
||
|
|
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| Time |
36 hrs post infection |
18 hrs post infection |
36 hrs post infection |
18 hrs post infection |
36 hrs post infection |
|
|
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| Control group (non-immunized) |
0 |
1.08 ± 0.14 × 106 |
8.98 ± 1.94 × 106 |
1.11 ± 0.20 × 108 |
2N/A |
| PBS |
0 |
4.92 ± 0.94 × 105 |
1.54 ± 0.94 × 106 |
3.16 ± 1.94 × 106 |
2N/A |
| IFA |
0 |
2.35 ± 1.12 × 105 |
1.23 ± 1.14 × 106 |
1.80 ± 0.22 × 106 |
2.16 ± 1.10 × 106 |
| PHIS-01 |
0 |
3.64 ± 1.44 × 105 |
1.13 ± 2.31 × 106 |
8.90 ± 3.20 × 105 |
5.60 ± 0.94 × 105 |
| PHYTOL |
0 |
4.0 ± 0.25 × 103 |
0 |
8.90 ± 1.12 × 104 |
0 |
|
1 Peritoneal fluid samples from all groups of mice were diluted in LB medium (1:200), and 10 μl of diluted samples were streaked on agar plates using calibrated loops. CFUs were scored 18 and 36 hours following bacterial challenge and recorded as CFU/ml. The results represent the average of two experiments (n = 4 for each group) ± SEM. 2 N/A: Not assessable since all mice were dead within 18 hrs. | |||||
Lim et al. Journal of Immune Based Therapies and Vaccines 2006 4:5 doi:10.1186/1476-8518-4-5 |
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