Table 2

Recovery of S. aureus from peritoneal fluid obtained from mice challegened with live S. aureus

Bacterial challenge (CFU)
106
107
108

Time
36 hrs post infection
18 hrs post infection
36 hrs post infection
18 hrs post infection
36 hrs post infection

Control group (non-immunized)
0
1.08 ± 0.14 × 106
8.98 ± 1.94 × 106
1.11 ± 0.20 × 108
2N/A
PBS
0
4.92 ± 0.94 × 105
1.54 ± 0.94 × 106
3.16 ± 1.94 × 106
2N/A
IFA
0
2.35 ± 1.12 × 105
1.23 ± 1.14 × 106
1.80 ± 0.22 × 106
2.16 ± 1.10 × 106
PHIS-01
0
3.64 ± 1.44 × 105
1.13 ± 2.31 × 106
8.90 ± 3.20 × 105
5.60 ± 0.94 × 105
PHYTOL
0
4.0 ± 0.25 × 103
0
8.90 ± 1.12 × 104
0

1 Peritoneal fluid samples from all groups of mice were diluted in LB medium (1:200), and 10 μl of diluted samples were streaked on agar plates using calibrated loops. CFUs were scored 18 and 36 hours following bacterial challenge and recorded as CFU/ml. The results represent the average of two experiments (n = 4 for each group) ± SEM. 2 N/A: Not assessable since all mice were dead within 18 hrs.

Lim et al. Journal of Immune Based Therapies and Vaccines 2006 4:5   doi:10.1186/1476-8518-4-5

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