|
Compare and contrast L-2 with HIV |
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| Protein |
L-2 |
HIV |
Virion |
L-2 |
HIV |
|
|
|||||
| Gag |
(+)* |
(+)** |
Genome RNA |
(+) |
(+) |
| Pol |
(-) |
(+) |
Infectivity |
(-) |
(+) |
| Vif |
(-) |
(+) |
Envelope Spikes |
7–10 times |
Normal |
| Vpr |
(-) |
(+) |
Particles |
Doughnut like |
Normal |
| Vpu |
(+) |
(+) |
Antigenicity |
(+) |
(+) |
| Tat |
(+) |
(+) |
CD4+ Cell Fusion |
Yes |
Yes |
| Rev |
(+) |
(+) |
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| Env |
(+) |
(+) |
|||
| Nef |
(-) |
(+) |
|||
|
* gag uncleaved ** gag cleaved | |||||
Zhong and Luftig Journal of Immune Based Therapies and Vaccines 2007 5:12 doi:10.1186/1476-8518-5-12 |
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