Table 1

Patient Characteristics (Intent-To-Treat Population)

Parameter
Engerix®-B
HBsAg alone
HBsAg + 3 μg IMP321
HBsAg + 10 μg IMP321
HBsAg + 30 μg IMP321
HBsAg + 100 μg IMP321

Number enrolled
8
8
9
9
8
8
Number completed
8
8
8
8
8
8
Age (years)a Mean ± SD
32.1 ± 11.2
41.0 ± 11.4
31.4 ± 8.0
29.0 ± 9.2*
37.3 ± 9.7
35.9 ± 7.4
Genderb






     Male
7
7
9
9
8
8
     Female
1
1
0
0
0
0
Raceb






     Caucasian
7
6
6
5
6
7
     Black
1
1
1
2
2
1
     Asian
0
0
1
1
0
0
     Other
0
1
1
1
0
0

a Student's t-test. * p < 0.05 compared to HBsAg alone control group.

b Chi-square. P >0.05 compared to HBsAg alone control group.

Brignone et al. Journal of Immune Based Therapies and Vaccines 2007 5:5   doi:10.1186/1476-8518-5-5