Table 1

Percent-number and mean ± SD of Stimulation-Indices in PBMC assays with BCGr32Kda protein in different categories of children.


Scar +ve
n = 45
Scar -ve
n = 45
TB
n = 25
P value

Mean (± SD) of positive SIs
4.9 ± 1.9a
2.9 ± 1.17b
2.9 ± 0.73c
p < 0.0004ab
p < 0.0014ac
Mean (± SD) of negative SIs
1.6 ± 0.29
1.6 ± 0.31
1.7 ± 0.20

%n with positive SI*
79
39
58

%n with negative SI*
21
61
42


Stimulation Indices (SI) < 2: negative & ≥ 2: positive in T cell assays.

Statistical analysis of the mean values of SIs was done by Student's t-test.

Chi-square test to compare number of children was done by cross tabulation method:

*Scar positive Vs. Scar negative, χ2 = 10.465; p < 0.001

* Scar positive Vs. Tuberculosis, χ2 = 3.630; p < 0.057

Anuradha et al. Journal of Immune Based Therapies and Vaccines 2007 5:8   doi:10.1186/1476-8518-5-8