Figure 1.

C57Bl/6 mice were immunized once, as described in the text, with ovalbumin and the adjuvant shown at the top of the figure, and bled at various days post-immunization (shown on left side of figure). ELISA data are plotted for 5 mice in each case with the reciprocal of the serum dilution on the x axis, and optical density at 490 nm on the y axis. Note the scale of the y axis varies by row. Response to CD40mAb adjuvanted vaccine was significantly better than the response to MPL or alum at day 7 (p < 0.05, One-way ANOVA with Dunnet's post-test).