Table 2 |
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|
Comparison of ratios of IgG2a to IgG1 in mice given either PCEP+X:31 or X:31 alone. |
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|
Formulation |
X:31 |
PCEP+X:31 |
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|
|
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|
Delivery route |
IgG2a |
IgG1 |
IgG2a/IgG1 ratio |
IgG2a |
IgG1 |
IgG2a/IgG1 ratio |
|
|
||||||
|
Intranasal |
3.73 |
4.19 |
0.89 |
5.95 |
6.04 |
0.99 |
|
Subcutaneous |
4.39 |
5.62 |
0.78 |
6.41 |
6.51 |
0.98 |
|
Oral |
2.29 |
3.47 |
0.66 |
3.95 |
4.48 |
0.88 |
|
Intrarectal |
3.65 |
4.35 |
0.84 |
3.74 |
4.67 |
0.80 |
|
|
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|
Mean serum titers at 8 weeks post-primary immunization were used for the calculations |
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|
Eng et al. Journal of Immune Based Therapies and Vaccines 2010 8:4 doi:10.1186/1476-8518-8-4 |
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