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1: APMIS. 2003 Jul-Aug;111(7-8):766-75.
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Dendritic cells in peripheral tolerance and immunity.

Gad M, Claesson MH, Pedersen AE.

Department of Medical Anatomy, The Panum Institute, University of Copenhagen, Copenhagen, Denmark.

Dendritic cells capable of influencing immunity exist as functionally distinct subsets, T cell-tolerizing and T cell-immunizing subsets. The present paper reviews how these subsets of DCs develop, differentiate and function in vivo and in vitro at the cellular and molecular level. In particular, the role of DCs in the generation of regulatory T cells is highlighted.

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PMID: 12974778 [PubMed - indexed for MEDLINE]