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Improved generation of anti-tumor immunity by antigen dose limitation.

Shofner JD, Vasquez JG, Berger CL, Edelson RL.

J Immune Based Ther Vaccines. 2007 Feb 9;5:2.

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Cutaneous T-cell lymphoma: malignant proliferation of T-regulatory cells.

Berger CL, Tigelaar R, Cohen J, Mariwalla K, Trinh J, Wang N, Edelson RL.

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Interaction of cutaneous lymphoma cells with reactive T cells and dendritic cells: implications for dendritic cell-based immunotherapy.

Thumann P, Lüftl M, Moc I, Bagot M, Bensussan A, Schuler G, Jenne L.

Br J Dermatol. 2003 Dec;149(6):1128-42.

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The life cycle of cutaneous T cell lymphoma reveals opportunities for targeted drug therapy.

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Development of immunogenic tumor-loaded dendritic cells through physical perturbation and apoptotic cell loading.

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The growth of cutaneous T-cell lymphoma is stimulated by immature dendritic cells.

Berger CL, Hanlon D, Kanada D, Dhodapkar M, Lombillo V, Wang N, Christensen I, Howe G, Crouch J, El-Fishawy P, Edelson R.

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Increased regulatory T cells correlate with CD8 T-cell impairment and poor survival in hepatocellular carcinoma patients.

Fu J, Xu D, Liu Z, Shi M, Zhao P, Fu B, Zhang Z, Yang H, Zhang H, Zhou C, Yao J, Jin L, Wang H, Yang Y, Fu YX, Wang FS.

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Proinflammatory mediator-induced reversal of CD4+,CD25+ regulatory T cell-mediated suppression in rheumatoid arthritis.

van Amelsfort JM, van Roon JA, Noordegraaf M, Jacobs KM, Bijlsma JW, Lafeber FP, Taams LS.

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Expression of human GITRL on myeloid dendritic cells enhances their immunostimulatory function but does not abrogate the suppressive effect of CD4+CD25+ regulatory T cells.

Tuyaerts S, Van Meirvenne S, Bonehill A, Heirman C, Corthals J, Waldmann H, Breckpot K, Thielemans K, Aerts JL.

J Leukoc Biol. 2007 Jul;82(1):93-105. Epub 2007 Apr 20.

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Downregulation of CD4+CD25+ regulatory T cells may underlie enhanced Th1 immunity caused by immunization with activated autologous T cells.

Cao Q, Wang L, Du F, Sheng H, Zhang Y, Wu J, Shen B, Shen T, Zhang J, Li D, Li N.

Cell Res. 2007 Jul;17(7):627-37.

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Expression of dendritic cell markers on cultured neutrophils and its modulation by anti-apoptotic and pro-apoptotic compounds.

Park HY, Jin JO, Song MG, Park JI, Kwak JY.

Exp Mol Med. 2007 Aug 31;39(4):439-49.

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Combination of tumor site-located CTL-associated antigen-4 blockade and systemic regulatory T-cell depletion induces tumor-destructive immune responses.

Tuve S, Chen BM, Liu Y, Cheng TL, Touré P, Sow PS, Feng Q, Kiviat N, Strauss R, Ni S, Li ZY, Roffler SR, Lieber A.

Cancer Res. 2007 Jun 15;67(12):5929-39.

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Transimmunization for cutaneous T cell lymphoma: a Phase I study.

Girardi M, Berger CL, Wilson LD, Christensen IR, Thompson KR, Glusac EJ, Edelson RL.

Leuk Lymphoma. 2006 Aug;47(8):1495-503.

PMID: 16966259 [PubMed - indexed for MEDLINE]

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Induction of immunosuppressive functions of dendritic cells in vivo by CD4+CD25+ regulatory T cells: role of B7-H3 expression and antigen presentation.

Mahnke K, Ring S, Johnson TS, Schallenberg S, Schönfeld K, Storn V, Bedke T, Enk AH.

Eur J Immunol. 2007 Aug;37(8):2117-26.

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Efficient tumor antigen loading of dendritic antigen presenting cells by transimmunization.

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CD4+FoxP3+ regulatory T cells gradually accumulate in gliomas during tumor growth and efficiently suppress antiglioma immune responses in vivo.

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Int J Cancer. 2007 Jul 1;121(1):95-105.

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Granzyme B and perforin are important for regulatory T cell-mediated suppression of tumor clearance.

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Immunity. 2007 Oct;27(4):635-46. Epub 2007 Oct 4.

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Rapamycin-conditioned dendritic cells are poor stimulators of allogeneic CD4+ T cells, but enrich for antigen-specific Foxp3+ T regulatory cells and promote organ transplant tolerance.

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J Immunol. 2007 Jun 1;178(11):7018-31.

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